The paper studies the possibility of remediation of soils contaminated with sodium fluoride, using natural sorbents-ameliorators. The study describes a model experiment for evaluating application efficiency of ameliorators in the soil contaminated with sodium fluoride, by analyzing the activity of redox and hydrolytic enzymes of soil. The study showed that the addition of sorbents (gypsum and activated carbon) in the soil contaminated with sodium fluoride, activated its enzymatic activity, which indicated the possibility of their application for the restoration of soils contaminated with fluoride.