Introduction. As part of the sanctions policy pursued by a number of foreign countries, the Russian government has introduced counter-sanctions measures as measures of protectionism. Import substitution has become a new reality for chemical industry enterprises. But protectionism has not created ideal conditions. There are also a number of problems that require the development of an acceptable strategy for the sustainable development of enterprises producing household chemicals. Goal. To consider the directions of developing a strategy for the development of chemical industry enterprises in the conditions of the modern political situation created by the USA and EU countries on the example of “NPF “GENIX” LLC. Materials and methods. The development of an enterprise development strategy was discussed on the basis of an assessment of materials published in open sources, a study of federal legislative acts and an analysis of the production and economic activities of the enterprise. The results of the study and discussion. In the context of the import substitution policy, the Russian government has defined the task for the domestic producer - to compensate for the lack of imported products with domestic goods. And this has become one of the most priority areas of development in Russia. But in the chemical industry sector, a problem arose for manufacturers of household chemicals, which resulted in a shortage of raw materials in the domestic market, which forced them to start looking for a solution to this problem. To overcome the problems, in the context of Western sanctions, it is necessary to develop a strategy for the development of the enterprise to reduce risks of an economic and administrative nature. It is necessary to achieve economic growth through the production of competitive products, the introduction of innovative and resource-saving technologies, and increased profitability. Conclusion. The problems that have arisen require solutions from the Government and the legislature. Therefore, specific actions are required, both at the regional and federal levels, it is necessary to develop a system of state orders for household chemicals, detergents and disinfectants, in particular, to provide the health care system, the catering sector, for the needs of the population and a state program to promote products to foreign markets.