Introduction. One of the problems of industrial animal husbandry is the quality of feed. Mycotoxins contained in feed are able to circulate through the food chain and pose a threat to human health. An additional risk factor is medicines (antiparasitic, antibacterial, etc.), residual amounts of which may be present in food. For this reason, the role of enterosorbents in animal husbandry is increasing. Purpose. To summarize the experience of using silicon dioxide in pig farming and evaluate the prospects for the creation of new medicines based on it. Materials and methods. The data was searched in eLIBRARY.RU, Scopus, Web of Science, and PubMed databases, where “sorbent”, “enterosorbent”, “pigs”, “silicon dioxide”, and “silica” were used as search words. The manuscript included articles describing various effects of enterosorbents and features of the action of silicon dioxide. Research results and discussion. The results of the use of silicon dioxide in pig farming have been demonstrated. Silicon dioxide improves the digestibility of nutrients, increases the productivity of animals, including the indicators of average daily growth and post-slaughter weight of pigs, and improves the reproductive function of sows. The ability of silicon dioxide to bind mycotoxins, as well as to improve the protein-synthesizing function of the liver, has been proven in laboratory and industrial conditions. At the same time, it has an antioxidant effect and exhibits antibacterial properties. When added to the diet of piglets, it reduces the amount of E. coli in the feces, and eliminates signs of diarrhea. Silicon dioxide can be used as a matrix for modification by various compounds, including antibacterial and antiparasitic drugs, which increases their pharmacological effectiveness at lower doses. Conclusion. Silicon dioxide is used as a multifunctional enterosorbent in pig breeding and is of interest as a matrix for the production of modified drugs with a wide range of pharmacological effects.