Most of the territory of the Republic of Mari El is occupied by acidic sod-podzolic soils and has low natural fertility. In this case searching for ecologically safe ways increasing productivity of crops and improving quality of products is a very necessary and practical task for the Republic. The purpose of our research was the identification of efficiency of using of the granulated organic fertilizers on productivity and grain quality of spring wheat. Chicken manure is a valuable concentrated complete fertilizer in terms of the content of nutrients and their availability for growing crops. The experimental part of the work was performed at the stationary site of the experimental field of the Mari Agricultural Research Institute – branch of the FASC of the North-East. The frequency of the experiment is 4-fold, the placement of the plots is systematic. As a test culture, the variety of spring wheat Simbircite was used, the predecessor in the crop rotation was winter rye. Studies have shown that the use of GOF based on poultry manure contributed to a decrease in the incidence of spring wheat root rot, beginning with booting phase on average for 0.5 % in comparison with other variants. It should be noted that at the rate of application of 100 kg/ha of granulated organic fertilizers contributed to a significant increase in the yield of spring wheat, which amounted to 4.08 t/ha, which is 16.6 % higher than the control. Also in the version with the use of GOF there was an increase in the gluten content by 28.8 %. In general, the results confirm the value of granulated organic fertilizers based on poultry manure. The application of this fertilizer enriches the soil with necessary nutrients, increasing the productivity and quality of grown-up crops.