Introduction. The standard of living of families with children is complex and ambiguous. This problem is due to the fact that in the Russian Federation there are a sufficient number of families with children living in poverty or even below the poverty line. Therefore, it is important to identify such problems and improve the quality of life of population groups that cannot independently solve the problems of family life support due to certain circumstances. The purpose of the research is to conduct a statistical analysis of child well-being in the Republic of Mari El, to determine the level of child well-being in the Republic of Mari El in the context of all subjects of the Russian Federation, to identify socio-economic indicators that affect the main indicators of child well-being and build scenario forecasts. Materials and methods. The published statistical data of the Federal State Statistics Service and the data of the project “To be precise” served as the information base for conducting the declared study. Multivariate cluster analysis methods, principal component analysis, as well as regression and time series forecasting methods were used as research tools. Results of the research, discussion. The article proposes a methodology for analyzing and predicting child well-being on the example of the Republic of Mari El, based on the use of cluster analysis methods for the principal components and various regression models. This approach allows you to determine the factors that determine child well-being in a particular area. Conclusion. The level of child well-being in the Republic of Mari El is quite low compared to other subjects of Russia, this is primarily due to the low income of families. Particular attention should be paid to such indicators as: the subsistence minimum for a child under the age of 16 (18), the number of children who received a regular financial aid and the income of households with children. To improve the quality of life of children, it is necessary to develop new social programs, support families economically, legally and socially, and follow existing programs, such as the Decade of Childhood, in this case, the well-being of children will develop in a positive dynamic.