In the context of the intensification of poultry farming and the multifactorial nature of the reasons affecting its profitability, it was necessary to develop new feed additives to maintain health and increase the productivity of poultry. The available feed additives did not always take into account the techno-logies of feeding and mainte-nance in poultry farming that had changed over the years, an increase in productivity and metabolic pressure on the poultry body, the risk of metabolic syndrome, which could be catalyzed by modern agricultural chemistry. The aim of the research was the primary selection of potential components for the development of a feed addi-tive in order to correct metabolism and increase the productivity of laying hens. Laying hens of the Lochmann cross, 260−320 days old, were formed into groups of 5 individuals each, 17 groups in total. Potential formula-tions which were given with food or with drinking water were tested for 20 days. Several series of experiments were carried out. During the experiment, the clinical picture of sick chickens was monitored, egg production was recorded, at the end of the test, a diagnostic autopsy and blood sampling for biochemical analysis of blood serum were carried out. One of the main criteria for evaluating the effectiveness of the additive was a change in the orange-red coloration of the droppings, as the main sign of a disease of unknown origin. Various formula-tions (13 variants) with ingredients with potential sorption, antioxidant, immunostimulating, hepatoprotective, metabolism and feed digestibility properties had been studied. As a result of screening, including an assessment of productivity, biochemical blood profile, color of droppings and defective eggs (spots), it was found that the most optimal recipe were coded P11 and P12.