In the article the technique of deduction method application when forming of the integrated modular indicators characterizing the extent of industrial production indicators influence of different types of activity of the Mari El Republic on the gross regional product is offered. The research of the time series of industrial production indexes in terms of structure stationarity and creation of a short-term forecast of volumes dynamics of the region industrial sector functioning provides the base at adoption of strategic solutions of rather perspective development of the Republic. Purpose: formation of integrated indicators of the industrial sphere and the forecast of industrial production indexes in the Republic of Mari El. Materials and methods. The statistical analysis of the industrial sector is carried out on the basis of analytical data of the Federal State Statistics Service in the Mari El Republic with application of methods of the factorial analysis and forecasting of the time series allowing to receive the generalized indicators of functioning of the region’s industry in total and to construct the short-term forecast of development dynamics for prospect. Results, discussion. The results of the formation of integrated indicators of the Mari El Republic industry demonstrate that the third factor (coefficient of informational content of the third principal components – 72,58 %), and the first factor (informational content coefficient – 68,12 %) have the greatest impact on the gross regional product volumes. It is provided due to modernization and technical re-equipment of productions, constant increased operating capacity at the enterprises of the types of industrial activity which are part of these factors. The enterprises recieve state support for subsidizing a part of leasing payments and a part of percentage expenses on the loans attracted for implementation of the investment projects aimed at the development of production and creation of new jobs. On the basis of point estimates of the forecast of the Republic industrial production indexes it is possible to draw a conclusion that from May, 2019 to January, 2020 the development trend in general is growing, the increase of industry volumes will reach 5,94 %. However, the presence of seasonality in the activities of industrial enterprises of the region leads to reduction of production activity of the industrial sector within the next 6 months for 7,98 % by June, 2020. In general, for the forthcoming 12 months the volumes of industrial activity in the Mari El Republic will increase by 8,16 % in comparison with the last period of similar extent. Conclusion. The technique of formation of the integrated indicators of the industrial sector development allows us to define the most perspective types of industrial activity providing significant growth of a gross regional product of the Mari El Republic. The offered short-term forecast of change of industrial production indexes gives an opportunity of operational impact on dynamics of the key defining industry indicators when forming strategic development plans for the region.