The article presents the results of scientific and economic experiment on studying the influence of feed additives, produced using local raw materials, on the metabolism of young animals of Kalmyk breed. The purpose of the research is to study the effect of feed additives, produced using local raw materials, on the digestibility and nutrient use of diets of young animals of beef breeds in Yakutia. The research work was carried out in the APC “Satabyl” of the Khangalassky ulus (region) of the Republic of Sakha (Yakutia). For carrying out scientific and business experiment, 4 groups of animals-analogues 10 animals each were formed taking into account age, body weight, and physiological state. Zootechnical analysis of feed chemical composition was studed in the laboratory for processing agricultural products and biochemical analysis of the FRC SB RAS YSRIA on the US NIRSCANER model 4250 analyzer. Nutrient use of rations by animals was determined by VIZh method, 1969. A balance experiment was carried out to determine the degree of influence of feed additives, produced using local raw materials (wheat “Prilenskaya 19”, barley “Tammi”, probiotic preparation “Sakhabactisubtil”), on the digestibility of ration nutrients. During the balance experiment, the amount of food eaten, their residues were taken into account, feces were collected. According to the scientific and economic experience, the diet of experimental groups in terms of energy nutrition corresponds to VIZh standards (1985). The difference in feeding was that the animals of the I-experimental group received brewer’s grains, mixed feed enriched with wheat “Prilenskaya 19” treated with “Sakhabaktisubtil” (10 ml), the II-experimental group received brewer’s grains, mixed feed enriched with barley “Tammi” processed with “Sakhabaktisubtil” (in the amount of 10 ml). The study on the use of feed additives produced using local raw materials: wheat “Prilenskaya 19”, barley “Tammi”, brewer's grains, the drug “Sakhabaktisubtil” and table salt balanced the diet for the missing nutrients and improved the palatability of the main feeds. Consumption of local feed additives by the young animals from the experimental groups led to small differences in nutrient digestibility ratios. At the same time, a high level of digestibility in young animals of the 1st experimental group as compared with the control and the 2nd experimental group was set for dry matter by 1.5 and 0.4 %; organic matter 1.4 and 0.1 %; crude protein by 2.1 and 1.2 %, crude fat by 1.8 and 1.0 % and crude fiber by 2.18 and 2.1 %, respectively.